{"title":"SAM-e","description":"SAM-e (S-Adenosyl methionine) is an amino acid derivative needed by the body for at least 40 biochemical reactions. It has a reputation as the most effective natural anti-depressant, without any of the unpleasant side effects of prescription drugs. It was first discovered in 1952 in Italy, and naturally occurs throughout the body when you are in good health. Aging processes, nutrient deficiency, sickness and depression can deplete SAM-e levels, indicating a need for supplementation.\n\u003ch3\u003eSAM-e Benefits\u003c\/h3\u003e\n\u003cp\u003eSAM-e is involved in the manufacture of hormones, cell membranes and mood regulating neurotransmitters. It is a potent mood elevator, energy enhancer, promoter of cell regeneration, neuromuscular balancer and joint mobiliser. It helps maintain cartilage and may support prevention and repair of liver damage.\u003c\/p\u003e\n\u003cp\u003eStudies show SAM-e may be effective in treating depression, fibromyalgia, joint pain, osteoarthritis, liver dysfunction and migraines.\u003c\/p\u003e\n\u003cp\u003eSAM-e is best taken alongside a vitamin B complex to maximise efficacy and prevent side effects.\u003c\/p\u003e\n\u003ch3\u003eSAM-e Side Effects and Contraindications\u003c\/h3\u003e\n\u003cp\u003eContraindicated when taking MAOI antidepressant medications. Contraindicated in cases of bipolar disorder unless under close medical supervision as it may promote the manic phase. Contraindicated in Parkinson’s disease as it may aggravate some symptoms. Possible side effects include gastrointestinal upsets: nausea, vomiting, diarrhoea, indigestion. Anxiety, headache, insomnia and allergies may also be experienced\u003c\/p\u003e","products":[{"product_id":"doctors-best-same-400mg-double-strength","title":"SAMe 400mg Double Strength","description":"\u003cp class=\"HealthPost\"\u003e\u003cstrong\u003eDoctor's Best SAMe 400mg Double Strength\u003c\/strong\u003e This is a double-strength SAM-e formula providing 400mg per tablet. \u003c\/p\u003e\u003cp class=\"HealthPost\"\u003e\u003cbr\u003eS-Adenosyl Methionine (SAM-e) is produced by the body from ATP and the amino acid methionine and is one of the most important methyl donors in the central nervous system. Methylation (donation of methyl groups) is an essential process in ensuring the proper function of a number of organ systems. SAM-e is involved in numerous biochemical reactions in tissue including the liver, joints and brain. SAM-e is also required for the synthesis of critical neurotransmitters and hormones. \u003cbr\u003e\u003cbr\u003eDoctor’s Best SAM-e has been shown to support a positive mood, brain health and mental focus. It is essential for the healthy metabolism of the major brain transmitters’ dopamine, serotonin and norepinephrine. In addition, SAM-e supports joint comfort and mobility as well as supporting liver health and detoxification. SAM-e effectiveness has been published in 18 controlled human studies published over 40 years. \u003cbr\u003e\u003cbr\u003eDoctor’s Best SAM-e uses pharmaceutical grade materials.  SAM-e is optimized for potency, stability, and to survive the stomach acid and reach the intestine (where it is absorbed).  \u003c\/p\u003e\u003cp\u003eTAPS PP1681\u003cbr\u003e \u003c\/p\u003e\u003cp class=\"HealthPost\"\u003e \u003c\/p\u003e\u003cp class=\"HealthPost\"\u003e \u003c\/p\u003e","brand":"Doctor's Best","offers":[{"title":"60 tablets","offer_id":47176520499418,"sku":"1110617-1","price":158.5,"currency_code":"NZD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0697\/2702\/7418\/files\/doctors-best-same-400mg-double-strength__49103.jpg?v=1764576025"},{"product_id":"doctors-best-same-200-mg","title":"SAMe 200 mg","description":"\u003cp\u003eS-Adenosyl Methionine (SAM-e) is produced by the body from ATP and the amino acid methionine and is one of the most important methyl donors in the central nervous system. Methylation (donation of methyl groups) is an essential process in ensuring the proper function of a number of organ systems. SAM-e is involved in numerous biochemical reactions in tissue including the liver, joints and brain. SAM-e is also required for the synthesis of critical neurotransmitters and hormones. \u003cbr\u003e\u003cbr\u003eDoctor’s Best SAM-e has been shown to support a positive mood, brain health and mental focus. It is essential for the healthy metabolism of the major brain transmitters’ dopamine, serotonin and norepinephrine. In addition, SAM-e supports joint comfort and mobility as well as supporting liver health and detoxification. SAM-e effectiveness has been published in 18 controlled human studies published over 40 years.  \u003cbr\u003e\u003cbr\u003eDoctor’s Best SAM-e uses pharmaceutical grade materials.  SAM-e is optimized for potency, stability, and to survive the stomach acid and reach the intestine (where it is absorbed). \u003c\/p\u003e\u003cp\u003e \u003c\/p\u003e\u003cp\u003eTAPs - PP1681\u003cbr\u003e \u003c\/p\u003e","brand":"Doctor's Best","offers":[{"title":"60 tablets","offer_id":47176697807066,"sku":"1110616-1","price":92.7,"currency_code":"NZD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0697\/2702\/7418\/files\/doctors-best-same-200-mg__01565.jpg?v=1764576022"},{"product_id":"now-foods-same-400mg","title":"SAMe 400mg","description":"\u003cspan style=\"font-weight: bold;\"\u003eNOW Foods SAMe 400mg\u003c\/span\u003e contains SAMe (S-adenosylmethionine), a compound native to the body, is a component of many biochemical reactions, including brain biochemistry and joint health. SAMe is critical for the synthesis of neurotransmitters, is important for energy production in the brain, supports the maintenance of healthy cell membrane function, and cartilage metabolism. Natural colour variation may occur in this product.\u003cdiv\u003e\u003cbr\u003e\u003c\/div\u003e\u003cdiv\u003eTAPS PP8119\u003cbr\u003e\n\u003c\/div\u003e","brand":"NOW foods","offers":[{"title":"30 tablets","offer_id":47217041735898,"sku":"1114257-1","price":72.4,"currency_code":"NZD","in_stock":true},{"title":"60 tablets","offer_id":47217041768666,"sku":"1114257-2","price":123.2,"currency_code":"NZD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0697\/2702\/7418\/files\/now-foods-same-400mg__93987.jpg?v=1766113159"}],"url":"https:\/\/www.healthpost.com.au\/collections\/sam-e.oembed","provider":"HealthPost","version":"1.0","type":"link"}